ABOUT plea

plea is a step towards antibiotic stewardship. Currently used antibiotics in clinical practice are important since they have evidence of use but due to rising resistance these important resources are becoming scarce. It is our duty to preserve
the effectiveness of existing antibiotics and thus contribute in reducing the mortality associated with
growing antimicrobial resistance.

We are committed to tackle antibiotic resistance by
preserving the life of existing antibiotics

preserving life of existing
antibiotics

Activities

  • Promoting research in the areas of Antibiotic Resistance Breaker (ARB) as an orthogonal strategy complimentary to new antibiotic discovery
  • Awareness on antibiotic use and abuse through Awareness Week on Antibiotic Knowledge and Education (AWAKE)
  • Platform for knowledge sharing amongst all stakeholders
  • Platform Antibiotic Stewardship
  • Partnering with various organisations across the globe to raise strong voice against antibiotic abuse

Hospital acquired Infections Management Program

We are on a mission to promote excellence in hospital practices by educating society and health care personnels to reduce the prevalence of Hospital Acquired Infections

Antibiotic resistance breakers

ARB’s are non antibiotic compounds that in combination with antibiotics enhance the antibacterial activity of the antibiotics

  • Alternative approach to novel antibiotic drug development
  • Working with known molecule with proven safety
  • Lesser Research Time
  • Relatively Lower Cost

AMR Surveillance Portal

A comprehensive software system for pan-India AMR surveillance program

Implemented through a vast network across 15 states, 250 districts through 150 centers including various Healthcare Institutions/Hospitals/Research Centers

Health Sanitation and Hygiene Awareness Program

This program focuses on health, sanitation and hygiene awareness in general public, school and colleges

Antibiotic Stewardship

The race against resistance is one that cannot be won solely by innovating new medicines. To truly combat this global resistance epidemic, a multipronged approach is required. Antimicrobial stewardship has been defined as "the optimal selection, dosage, and duration of antimicrobial treatment that results in the best clinical outcome for the treatment or prevention of infection, with minimal toxicity to the patient and minimal impact on subsequent resistance.

Preservation & Innovation

  • Re-engineering existing molecules to revive efficacy
  • Research and innovation to develop newer classes of drugs
  • Research into new and more reliable diagnostic tools and alternative therapies

Prevention

  • Establish robust surveillance mechanisms to capture resistance trends
  • Ensure apposite hospital hygiene to improve hospital ecology
  • Spreading awareness on the correct use of antibiotics

Appropriate use

  • Introduce preauthorization audits to ensure ethical disbursement of antibiotics
  • Follow adept clinical guidelines to prevent spread of resistance
  • Encourage express diagnostic testing to ascertain the cause of infection

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